The show is opened with a "bounty hunter" sequence featuring our host, then chronicles the emergence of the Indo-Pacific Lionfish as an Invasive Species in the western Atlantic, Gulf of Mexico and the Caribbean Sea. Filmed on location in the Virgin Islands, Belize, Key West, Corpus Christi, Egypt, Solomon Islands, and the Philippines. The documentary features interviews with famed oceanographer, Dr. Sylvia Earle, and Eugene "Rod" Roddenberry.